Potassium, Sodium & Iron

Three-mineral potassium, sodium and iron reference formula with 70 mg, 10 mg and 1.4 mg of the elements per serving, developed as a powder.

Potassium, Sodium & Iron is a reference formula for brands building a mineral premix for powder products, with example amounts of 70 mg of potassium, 10 mg of sodium and 1.4 mg of iron per serving. The reference labels pair the three minerals with a soluble fiber base, and the default label is a 14 g powder serving with 6 g of dietary fiber, so the three minerals are the module a brand adds to a fiber or drink powder base.

Powder is the only format because the premix is blended into a fiber or drink base. The development work centers on three mineral salts, the taste of potassium and iron in a powder, and the small weight of the premix compared with the base.

Ingredient Composition

IngredientPer ServingRaw Material FormAlternative Form (same amount of active)
Potassium70 mg (example amount)Potassium chloride, 133.5 mg per serving (52.4% potassium); specification purity and particle size set with the supplierPotassium citrate or potassium bicarbonate, each with its own potassium share and taste
Sodium10 mg (example amount)Sodium chloride, 25.4 mg per serving (39.3% sodium); specification purity and anti-caking agent set with the supplierSodium citrate, which gives a milder taste at the same sodium amount
Iron1.4 mg (example amount)Ferrous bisglycinate, 5.1 mg per serving (27.4% iron); specification iron content set with the supplierFerrous fumarate, which has a higher iron share and a stronger metallic note

Amounts are stated as mg of the element. Each raw material weight equals the labeled amount divided by the element share of the salt: potassium chloride KCl at 74.55 g/mol with potassium at 39.10 g/mol PubChem, sodium chloride NaCl at 58.44 g/mol with sodium at 22.99 g/mol PubChem, and ferrous glycinate C4H8FeN2O4 at 203.96 g/mol PubChem with iron at 55.84 g/mol PubChem.

Intended Benefits & Formula Rationale

This formula is designed for products positioned around mineral and electrolyte nutrition in powder form. The three minerals are included together because the reference labels carry them together in a powder serving.

Intended Benefit DirectionKey IngredientsFormulation Rationale
Iron nutritionIronA review of iron deficiency reports that it is one of the leading contributors to the global burden of disease, that oral iron is the first-line treatment in most cases, and that hepcidin upregulation limits absorption of high-dose oral iron [1]. Evidence: Referenced
Potassium nutritionPotassiumA dose-response meta-analysis of randomized trials found a U-shaped relationship between potassium intake and blood pressure, and concluded that an adequate potassium intake is desirable while excessive supplementation should be avoided [2]. Evidence: Referenced

Amount, claims and target market are brand decisions reviewed for each sales market, and the sodium amount follows the brand’s electrolyte concept.

Available Formats

Powder is the only version built here, and the serving size follows the reference label.

FormatUnitPer ServingPack SizeOther Ingredients (typical)Suitability
Powder1 serving of 14 g70 mg potassium, 10 mg sodium, 1.4 mg iron30 sachets or a 420 g tubSoluble fiber base, sweetener, flavor, anti-caking agentMineral premix blended into a fiber or drink base

Raw Material Input & Fill (Design Estimate)

Design estimates. The input is the labeled weight of each mineral divided by the element share of its salt, with every salt assumed at 100% purity as purchased; the 14 g serving follows the reference label.

FormatRaw Material Input per UnitDesign FillBalance for ExcipientsVerification Before Scale-Up
Powder133.5 mg potassium chloride, 25.4 mg sodium chloride, 5.1 mg ferrous bisglycinate14000 mg per serving13836 mg basePremix uniformity, mineral assays, taste, dispersion

Capsule, tablet and liquid versions are separate projects, because the premix is built around a bulk fiber base, and a liquid version needs its own solution and preservation work.

Formulation Considerations

Iron at a very small amount. At 5.1 mg of chelate in a 14 g serving, iron has the least margin for segregation, so the premix is made as a pre-blend with part of the base and then added to the bulk.
Taste of the minerals. Potassium chloride has a bitter, salty edge, and iron adds a metallic note. A chelate form keeps the metallic note low, and the sweetener and flavor system is built around both.
Potassium limit. Dietary supplements typically limit potassium to 99 mg per unit [4], so the example amount of 70 mg sits under that figure, and the review in [2] advises against excessive potassium supplementation.
Sodium amount. A review of sodium intake and hypertension reports that a reduction in dietary sodium decreases blood pressure and the incidence of hypertension [3], so the sodium amount is a concept decision. Each sales market’s dose limit and label wording are reviewed before development.

Customization Options

Brands adjust the amount of each mineral, the salts, the base and the flavor.

ParameterRangeNote
Potassium per serving20 to 281 mgExamples span low to high electrolyte concepts; amounts above 99 mg need a market review
Sodium per serving5 to 340 mgChanges the salty note and the electrolyte profile
Iron per serving0.4 to 3 mgChanges the chelate weight and the metallic note
Salt formChloride, citrate, bisglycinateChanges the input weight, taste and solubility
BaseSoluble fiber or drink mixSets the serving size and the flavor system

The pilot run confirms premix uniformity across the bulk, the taste and color of the iron chelate in the finished flavor, and the assay of each mineral in the first units against the specification.

Flavor Options

FormatSuggested FlavorsWhy
PowderOrange, lemon-lime, berryCitrus and berry profiles cover the bitter-salty and metallic notes of the minerals

Technical Status & Data Sources

ItemStatusDetails
Reference formulaNIH DSLDThe ingredient and amount come from a labeled product in the NIH DSLD (Potassium 70 mg + Sodium 10 mg + Iron 1.4 mg on the label of CF011136; example DSLD labels 82674, 178597, 179109). The label lists potassium, sodium and iron within a powder that also carries dietary fiber; salts are set as the forms.
SpecificationSet in formulationPotassium chloride, sodium chloride and ferrous bisglycinate supplying the labeled elemental amounts; element content, heavy-metal limits and assay method are fixed with the supplier. Unit size, fill weight and stability are set in formulation.
Data sourceNIH DSLDDSLD v9.4.0, downloaded 2026-01-10: 50,824 reference formulas merged from on-market labels with complete ingredient amounts. Counts show how labels are distributed.
Market reviewPer marketDose limits, labeling and claims are reviewed for each sales market before a finished product is developed.
ReferencesSources[1] Pasricha SR, Tye-Din J, Muckenthaler MU, Swinkels DW. Iron deficiency. Lancet. 2021;397(10270):233-248. DOI32594-0) · PubMed<br>[2] Filippini T, Naska A, Kasdagli MI, et al. Potassium intake and blood pressure: a dose-response meta-analysis of randomized controlled trials. J Am Heart Assoc. 2020;9(12):e015719. DOI · PubMed<br>[3] Grillo A, Salvi L, Coruzzi P, Salvi P, Parati G. Sodium intake and hypertension. Nutrients. 2019;11(9):1970. DOI · PubMed<br>[4] National Institutes of Health, Office of Dietary Supplements. Potassium: fact sheet for health professionals. Link

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