Garcinia Cambogia Extract

Garcinia cambogia fruit rind extract reference formula at an example amount of 500 mg per serving, developed as a capsule or powder.

Garcinia Cambogia is a reference formula for brands building a single-ingredient garcinia cambogia extract product around an example amount of 500 mg per serving. The brand sets the final amount for its market, and reference labels span 250 to 3,000 mg per serving, so the example is a starting point rather than a standard.

Capsule is the lead format because most reference labels use it, with a powder version developed for brands that prefer a scoop. The work centers on the extract: its hydroxycitric acid (HCA) content and salt form decide the specification, and a market-by-market safety review is part of the plan from the start.

Ingredient Composition

IngredientPer ServingRaw Material FormAlternative Form (same amount of active)
Garcinia Cambogia500 mg (example amount)Garcinia cambogia Extract 50–60% HCA, the fruit rind extract specified by hydroxycitric acid content; 500 mg extract per servingGarcinia Cambogia Extract Powder, with the HCA content and the salt form stated on the specification

The amount is stated as mg of extract. The reference label gives no HCA percentage, so the grade is set in formulation; the HCA per serving follows from the extract weight and its assay, and the specification states whether HCA is bound as a calcium, potassium or mixed salt.

Intended Benefits & Formula Rationale

This formula is designed for products positioned around weight and metabolic nutrition programs. Garcinia cambogia is included as the single botanical so that the concept stays on one extract.

Intended Benefit DirectionKey IngredientsFormulation Rationale
Lipid markers in studiesGarcinia CambogiaA meta-analysis of 14 trials with 623 subjects reports that Garcinia cambogia use reduced total cholesterol (−6.76 mg/dL) and triglycerides (−24.21 mg/dL) and raised HDL cholesterol (+2.95 mg/dL), without a significant effect on LDL cholesterol, and its authors note short interventions and significant heterogeneity [1]. Evidence: Referenced

The amount is an example. The meta-analysis in [1] pools trials of different doses and extracts and does not test this formula, so any claim on a finished product is reviewed for each market.

Available Formats

Reference labels are mostly capsules, with a smaller group of powders; capsule and powder are developed here.

FormatUnitPer ServingPack SizeOther Ingredients (typical)Suitability
Capsule1 vegetarian capsuleGarcinia cambogia extract 500 mg60 or 120 capsulesVegetable cellulose capsule shell, microcrystalline cellulose, gum acacia, ascorbyl palmitateLead format; one capsule per serving
Powder1 scoop, 3 gGarcinia cambogia extract 500 mg90 g tub (30 servings)Sweetener, acid, flavor, flow agentDrink mix; sour taste needs masking

Raw Material Input & Fill (Design Estimate)

Design estimates. The extract is taken at its declared weight, so 500 mg per serving needs 500 mg of extract; the HCA content applied to the label is the supplier’s assay once the grade is chosen.

FormatRaw Material Input per UnitDesign FillBalance for ExcipientsVerification Before Scale-Up
Capsule500 mg560 mg per capsule60 mgHCA assay, flow of a hygroscopic extract, capsule weight spread, shell opening time
Powder500 mg3 g per scoop2,500 mgHCA assay in the finished mix, dissolution, taste, caking

Tablet, liquid and gummy are separate projects, because a hygroscopic acidic extract changes compression, stability and taste work in those systems.

Formulation Considerations

Hygroscopic extract. Garcinia extracts attract moisture and turn sticky, which affects flow in a capsule filler and caking in the tub. Humidity-controlled filling, a flow agent and a desiccant are tested in the pilot run.
HCA grade and salt. Extracts are sold at different HCA percentages and as calcium, potassium or mixed salts. The grade changes the HCA per serving, the mineral content and the cost, and the specification names the one chosen.
Safety review. A letter reviewing the literature reports different cases of acute liver injury after the use of food supplements containing Garcinia cambogia and hydroxycitric acid and calls for a safe use of these supplements [2]. The market review, the label warnings and the recommended serving are therefore settled with the safety evaluation before any batch.
Acidic taste. The extract is sour. Capsules hide it, and the powder format needs a sweetener and flavor system that is tested in water.

Customization Options

Brands adjust the amount, the grade, the format and the add-ons.

ParameterRangeNote
Extract per serving500, 1000 or 1500 mgExamples for the brand; checked against the safety review before use
HCA gradeBy supplier rangeChanges the active per serving and the mineral content
FormatCapsule or powderTablet, liquid and gummy are separate projects
Add-onsChromium, green tea extractChromium or green tea adds fill weight and needs its own label review

The pilot run confirms the HCA assay against the label, the flow of the extract in the capsule filler, and the taste of the powder in water.

Flavor Options

FormatSuggested FlavorsWhy
PowderPeach, tropical, berrySweet fruit flavors cover the sour note

Technical Status & Data Sources

ItemStatusDetails
Reference formulaNIH DSLDThe ingredient and amount come from a labeled product in the NIH DSLD (500 mg on the label of CF013418; example DSLD labels 200651, 210683, 232012). The label names the ingredient as garcinia cambogia extract and states no HCA percentage; the grade is set in formulation.
SpecificationSet in formulationGarcinia cambogia fruit rind extract at 500 mg per serving with a stated HCA content and salt form; assay, moisture, microbial and heavy-metal limits and method are fixed with the supplier. Unit size, fill weight and stability are set in formulation.
Data sourceNIH DSLDDSLD v9.4.0, downloaded 2026-01-10: 50,824 reference formulas merged from on-market labels with complete ingredient amounts. Counts show how labels are distributed.
Market reviewPer marketDose limits, labeling and claims are reviewed for each sales market before a finished product is developed.
ReferencesSources[1] Amini MR, Rasaei N, Jalalzadeh M, et al. The effects of Garcinia cambogia (hydroxycitric acid) on lipid profile: A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2024;38(2):1028-1043. DOI · PubMed<br>[2] Zovi A, Langella R, Nisic A, et al. Liver injury and dietary supplements: Does hydroxycitric acid trigger hepatotoxicity? J Integr Med. 2022;20(5):473-475. DOI · PubMed

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